Molecular Orthopaedics - What is it
Molecular biology in orthopaedics is an evolving branch. It encompasses learning about gene expressions in various orthopaedic disorders to aspects of experimental treatment developments which include gene therapy for Arthritis.
Experimental treatments
- Intra articular transfer of IL-1 receptor antagonist (IL-1Ra) cDNA reduces disease in animal models of RA.
- Regional gene therapy to enhance bone repair
There are various centres which are pioneering in this field including
- Centre for Molecular Orthopaedics
- University of Hospitals Chicago Molecular orthopaedics department
- University of California, San Francisco Orthopaedic Trauma Institute Molecular biology lab
- Institute of Bioengineering and Nanotechnology, Singapore
There is also Society for Molecular Orthopaedics called
Books about Molecular Orthopaedics
- Molecular Biology in Orthopaedics (synosium) by Randy N. Rosier, MD, PhD and Christopher H. Evans, PhD, DSc, Editors
Websites about Molecular Orthopaedics
Tags: Bioengineering, Bone Repair, cDNA, Gene Therapy, IL-1Ra, IL1, Molecular Orthopaedics, Molecular Orthopedics, Nanotechnology, Orthopaedics
July 21st, 2008 at 11:09 pm
[...] Penna has an intro to Molecular Orthopaedics - What is it (orthopedists are getting [...]
July 22nd, 2008 at 12:00 pm
Very exciting for the future - thanks…jc
July 22nd, 2008 at 9:49 pm
It is a strange time in orthopaedics. We can do more than ever for patients. There is the real possibility we can cure osteoarthritis in the next decade or two. The knee and hip implants are better than ever. The advances on the cellular and molecular level are astounding (was nonexistent or just starting when I was a resident 15 years ago).
But why are we so frustrated with practicing medicine?
Insurance and patient’s demands, I suspect.